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responses_to_ai:technological_inevitability:incentivized_technologies_not_pursued:vaccine_challenge_trials [2023/04/04 17:29] jeffreyheninger |
responses_to_ai:technological_inevitability:incentivized_technologies_not_pursued:vaccine_challenge_trials [2023/04/05 21:17] jeffreyheninger |
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Human challenge trials for vaccines involve giving volunteers vaccine candidates, then deliberating exposing them to the disease, to test the efficacy of a vaccine candidate more quickly than standard vaccine trials. | Human challenge trials for vaccines involve giving volunteers vaccine candidates, then deliberating exposing them to the disease, to test the efficacy of a vaccine candidate more quickly than standard vaccine trials. | ||
- | Challenge trials are not a technological temptation which has been fully resisted: they have been used for dozens of diseases, including some recently. They are a technological temptation which has been significantly slowed in response to ethical concerns. | + | Challenge trials are not a technological temptation which has been fully resisted: they have been used for dozens of diseases, including some recently. They have been significantly slowed in response to ethical concerns. |
- | For COVID-19, if challenge trials had been done faster, we estimate that they could have allowed vaccines to be developed a few months more quickly. The value resisted by slowing this technological temptation is trillions of dollars and hundreds of thousands or millions of lives lost. | + | For COVID-19, if challenge trials had been done faster, we estimate that they could have allowed vaccines to be developed a few months more quickly, which could have saved trillions of dollars and hundreds of thousands or millions of lives lost. |
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